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So delicate is the fine tracery of the nervous structure, that the damage of a single fibre or a set of fibres destroys the unity of the whole. It is like a grand orchestra, in which one instrument alone out of time or tune disturbs the harmony of the rest, and the finest musical composition in the world is entirely spoiled by its discord. And this serious evil is apparent, not only in old age, but even in the young, in whom the disastrous consequences of injury to the brain, etc., are far more important both to themselves and to the world. - [Nerve]
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